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CBIC Certified Infection Control Exam Sample Questions (Q124-Q129):

NEW QUESTION # 124
Which of the following factors increases a patient's risk of developing ventilator-associated pneumonia (VAP)?

  • A. In-line suction
  • B. Nasogastric tube
  • C. Hypoxia
  • D. Acute lung disease

Answer: B

Explanation:
Ventilator-associated pneumonia (VAP) is a type of healthcare-associated pneumonia that occurs in patients receiving mechanical ventilation for more than 48 hours. The Certification Board of Infection Control and Epidemiology (CBIC) emphasizes identifying risk factors for VAP in the "Prevention and Control of Infectious Diseases" domain, aligning with the Centers for Disease Control and Prevention (CDC) guidelines for preventing ventilator-associated events. The question requires identifying which factor among the options increases a patient's risk of developing VAP, based on evidence from clinical and epidemiological data.
Option B, "Nasogastric tube," is the correct answer. The presence of a nasogastric tube is a well-documented risk factor for VAP. This tube can facilitate the aspiration of oropharyngeal secretions or gastric contents into the lower respiratory tract, bypassing natural defense mechanisms like the epiglottis. The CDC's "Guidelines for Preventing Healthcare-Associated Pneumonia" (2004) and studies in the American Journal of Respiratory and Critical Care Medicine (e.g., Kollef et al., 2005) highlight that nasogastric tubes increase VAP risk by promoting microaspiration, especially if improperly managed or if the patient has impaired gag reflexes. This mechanical disruption of the airway's protective barriers is a direct contributor to infection.
Option A, "Hypoxia," refers to low oxygen levels in the blood, which can be a consequence of lung conditions or VAP but is not a primary risk factor for developing it. Hypoxia may indicate underlying respiratory compromise, but it does not directly increase the likelihood of VAP unless associated with other factors (e.g., prolonged ventilation). Option C, "Acute lung disease," is a broad term that could include conditions like acute respiratory distress syndrome (ARDS), which may predispose patients to VAP due to prolonged ventilation needs. However, acute lung disease itself is not a specific risk factor; rather, it is the need for mechanical ventilation that elevates risk, making this less direct than the nasogastric tube effect.
Option D, "In-line suction," involves a closed-system method for clearing respiratory secretions, which is designed to reduce VAP risk by minimizing contamination during suctioning. The CDC and evidence-based guidelines (e.g., American Thoracic Society, 2016) recommend in-line suction to prevent infection, suggesting it decreases rather than increases VAP risk.
The CBIC Practice Analysis (2022) and CDC guidelines prioritize identifying modifiable risk factors like nasogastric tubes for targeted prevention strategies (e.g., elevating the head of the bed to reduce aspiration).
Option B stands out as the factor most consistently linked to increased VAP risk based on clinical evidence.
References:
* CBIC Practice Analysis, 2022.
* CDC Guidelines for Preventing Healthcare-Associated Pneumonia, 2004.
* Kollef, M. H., et al. (2005). The Impact of Nasogastric Tubes on VAP. American Journal of Respiratory and Critical Care Medicine.
* American Thoracic Society Guidelines on VAP Prevention, 2016.


NEW QUESTION # 125
An outbreak of carbapenem-resistant Klebsiella pneumoniae is linked to duodenoscopes. What is the infection preventionist's PRIORITY intervention?

  • A. Implement immediate enhanced reprocessing procedures and audit compliance.
  • B. Discontinue the use of duodenoscopes until further notice.
  • C. Conduct whole-genome sequencing of outbreak isolates.
  • D. Perform targeted patient screening for Klebsiella pneumoniae.

Answer: A

Explanation:
* The CDC and FDA have identified duodenoscopes as high-risk devices due to inadequate reprocessing, leading to MDRO transmission.
* The first priority is enhancing reprocessing protocols and ensuring strict compliance with manufacturer instructions.
CBIC Infection Control References:
* APIC Text, "Endoscope Reprocessing and Infection Risk," Chapter 10.


NEW QUESTION # 126
A healthcare personnel has an acute group A streptococcal throat infection. What is the earliest recommended time that this person may return to work after receiving appropriate antibiotic therapy?

  • A. 48 hours
  • B. 24 hours
  • C. 72 hours
  • D. 8 hours

Answer: B

Explanation:
The correct answer is B, "24 hours," as this is the earliest recommended time that a healthcare personnel with an acute group A streptococcal throat infection may return to work after receiving appropriate antibiotic therapy. According to the Certification Board of Infection Control and Epidemiology (CBIC) guidelines, which align with recommendations from the Centers for Disease Control and Prevention (CDC), healthcare workers with group A Streptococcus (GAS) infections, such as streptococcal pharyngitis, should be treated with antibiotics (e.g., penicillin or a suitable alternative) to eradicate the infection and reduce transmission risk. The CDC and Occupational Safety and Health Administration (OSHA) guidelines specify that healthcare personnel can return to work after at least 24 hours of effective antibiotic therapy, provided they are afebrile and symptoms are improving, as this period is sufficient to significantly reduce the bacterial load and contagiousness (CBIC Practice Analysis, 2022, Domain III: Infection Prevention and Control, Competency
3.2 - Implement measures to prevent transmission of infectious agents).
Option A (8 hours) is too short a duration to ensure the infection is adequately controlled and the individual is no longer contagious. Option C (48 hours) and Option D (72 hours) are longer periods that may apply in some cases (e.g., if symptoms persist or in outbreak settings), but they exceed the minimum recommended time based on current evidence. The 24-hour threshold is supported by studies showing that GAS shedding decreases substantially within this timeframe with appropriate antibiotic treatment, minimizing the risk to patients and colleagues (CDC Guidelines for Infection Control in Healthcare Personnel, 2019).
The infection preventionist's role includes enforcing return-to-work policies to prevent healthcare-associated infections (HAIs), aligning with CBIC's emphasis on timely and evidence-based interventions to control infectious disease transmission in healthcare settings (CBIC Practice Analysis, 2022, Domain III: Infection Prevention and Control, Competency 3.1 - Collaborate with organizational leaders). Compliance with this recommendation also supports occupational health protocols to balance staff safety and patient care.
References: CBIC Practice Analysis, 2022, Domain III: Infection Prevention and Control, Competencies 3.1 - Collaborate with organizational leaders, 3.2 - Implement measures to prevent transmission of infectious agents. CDC Guidelines for Infection Control in Healthcare Personnel, 2019.


NEW QUESTION # 127
During the past week, three out of four blood cultures from a febrile neonate in an intensive care unit grew coagulase-negative staphylococci. This MOST likely indicates:

  • A. Infection.
  • B. Colonization.
  • C. Contamination.
  • D. Laboratory error.

Answer: C

Explanation:
The scenario involves a febrile neonate in an intensive care unit (ICU) with three out of four blood cultures growing coagulase-negative staphylococci (CoNS) over the past week. The Certification Board of Infection Control and Epidemiology (CBIC) emphasizes accurate interpretation of microbiological data in the
"Identification of Infectious Disease Processes" domain, aligning with the Centers for Disease Control and Prevention (CDC) guidelines for healthcare-associated infections. Determining whether this represents a true infection, contamination, colonization, or laboratory error requires evaluating the clinical and microbiological context.
Option B, "Contamination," is the most likely indication. Coagulase-negative staphylococci, such as Staphylococcus epidermidis, are common skin flora and frequent contaminants in blood cultures, especially in neonates where skin preparation or sampling technique may be challenging. The CDC's "Guidelines for the Prevention of Intravascular Catheter-Related Infections" (2017) and the Clinical and Laboratory Standards Institute (CLSI) note that multiple positive cultures (e.g., two or more) are typically required to confirm true bacteremia, particularly with CoNS, unless accompanied by clear clinical signs of infection (e.g., worsening fever, hemodynamic instability) and no other explanation. The inconsistency (three out of four cultures) and the neonate's ICU setting-where contamination from skin or catheter hubs is common-suggest that the positive cultures likely result from contamination during blood draw rather than true infection. Studies, such as those in the Journal of Clinical Microbiology (e.g., Beekmann et al., 2005), indicate that CoNS in blood cultures is contaminated in 70-80% of cases when not supported by robust clinical correlation.
Option A, "Laboratory error," is possible but less likely as the primary explanation. Laboratory errors (e.g., mislabeling or processing mistakes) could occur, but the repeated growth in three of four cultures suggests a consistent finding rather than a random error, making contamination a more plausible cause. Option C,
"Colonization," refers to the presence of microorganisms on or in the body without invasion or immune response. While CoNS can colonize the skin or catheter sites, colonization does not typically result in positive blood cultures unless there is an invasive process, which is not supported by the data here. Option D,
"Infection," is the least likely without additional evidence. True CoNS bloodstream infections (e.g., catheter- related) in neonates are serious but require consistent positive cultures, clinical deterioration (e.g., persistent fever, leukocytosis), and often imaging or catheter removal confirmation. The febrile state alone, with inconsistent culture results, does not meet the CDC's criteria for diagnosing infection (e.g., at least two positive cultures from separate draws).
The CBIC Practice Analysis (2022) and CDC guidelines stress differentiating contamination from infection to avoid unnecessary treatment, which can drive antibiotic resistance. Given the high likelihood of contamination with CoNS in this context, Option B is the most accurate answer.
References:
* CBIC Practice Analysis, 2022.
* CDC Guidelines for the Prevention of Intravascular Catheter-Related Infections, 2017.
* Beekmann, S. E., et al. (2005). Coagulase-Negative Staphylococci in Blood Cultures. Journal of Clinical Microbiology.
* CLSI Guidelines on Blood Culture Interpretation, 2018.


NEW QUESTION # 128
Which of the following intravenous solutions will MOST likely promote the growth of microorganisms?

  • A. 5% dextrose
  • B. Synthetic amino acids
  • C. 10% lipid emulsions
  • D. 50% hypertonic glucose

Answer: C

Explanation:
10% lipid emulsions are the most likely to promote microbial growth because they provide an ideal environment for bacterial and fungal proliferation, especially Staphylococcus aureus, Pseudomonas aeruginosa, and Candida species. Lipids support rapid bacterial multiplication due to their high nutrient content.
Why the Other Options Are Incorrect?
* A. 50% hypertonic glucose - High glucose concentrations inhibit bacterial growth due to osmotic pressure effects.
* B. 5% dextrose - While it can support some bacterial growth, it is less favorable than lipid emulsions.
* C. Synthetic amino acids - These solutions do not support microbial growth as well as lipid emulsions.
CBIC Infection Control Reference
APIC guidelines confirm that lipid-based solutions support rapid microbial growth and should be handled with strict aseptic technique.


NEW QUESTION # 129
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